Deflazacort
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
441.52
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: Deflazacort
Alias: Calcort, Emflaza, Deflanil
CAS No: 14484-47-0
Molecular Formula: C25H31NO6
Molecular Weight: 441.52
Classification: Glucocorticoid, anti-inflammatory, immunosuppressant
Physical & Chemical Properties
Appearance: White crystalline powder
Melting Point: 255-256.5℃
Density: 1.41 g/cm3
Solubility: Soluble in acetic acid, dichloromethane; sparingly soluble in methanol, acetone; insoluble in water
Stability: Stable under normal temperature; avoid strong acid/alkali
Specification Table
| Item | Specification | Unit | Remarks |
| Product Name | Deflazacort | - | API grade |
| CAS No | 14484-47-0 | - | Pharmaceutical raw material |
| Appearance | White crystalline powder | - | Odorless |
| Molecular Formula | C25H31NO6 | - | Digital letter format |
| Molecular Weight | 441.52 | g/mol | - |
| Purity | ≥98.0 | % | HPLC |
| Moisture | ≤0.5 | % | - |
| Specific Rotation | +62.3° (c=0.5, CHCl3) | - | Chiral purity |
Main Uses
- Anti-inflammatory & immunosuppressive: Treats rheumatoid arthritis, lupus, nephrotic syndrome, allergies.
- Rare disease: Approved for Duchenne Muscular Dystrophy (DMD) in patients ≥2 years old.
- Organ transplantation: Prevents rejection as an immunosuppressant.
- Other indications: Adrenal insufficiency, skin diseases, eye disorders, ulcerative colitis.
Mode of Action
- Prodrug: Metabolized in vivo to 21-desacetyldeflazacort, the active form.
- Potency: ~70–90% of prednisone; lower mineralocorticoid activity reduces edema/hypertension risk.
