Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: Escitalopram oxalate
Alias: S-(+)-Citalopram oxalate; 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
CAS No: 219861-08-2
Molecular Formula: C??H??FN?O? (C??H??FN?O·C?H?O?)
Molecular Weight: 414.43
Classification: Chiral antidepressant; Selective Serotonin Reuptake Inhibitor (SSRI); Pharmaceutical API
Physical & Chemical Properties
Appearance: White or off-white crystalline powder
Melting Point: 148–154 °C (dec.)
Specific Rotation: +11.5° ~ +13.5° (c=1, methanol)
Solubility: Freely soluble in methanol; soluble in water; slightly soluble in ethanol
Stability: Hygroscopic; light-sensitive; store at 2–8 °C, sealed, dry
Specification Table
| Item | Specification | Unit | Remarks |
| Product Name | Escitalopram oxalate | — | Pharma grade |
| CAS No | 219861-08-2 | — | API |
| Appearance | White crystalline powder | — | Fine crystal |
| Molecular Formula | C??H??FN?O? | — | Chiral SSRI |
| Molecular Weight | 414.43 | g/mol | — |
| Purity | ≥98.5 | % | HPLC (USP/EP) |
| Enantiomeric Purity | ≥99.8 | % | Chiral HPLC |
| Loss on Drying | ≤0.5 | % | 105 °C, 2 h |
| Residual Solvents | MeOH ≤3000; EtOH ≤5000 | ppm | GC |
Main Uses
- Antidepressant API: Single-enantiomer (S-form) of Citalopram, high selectivity for 5-HT reuptake.
- Indications: Major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder with/without agoraphobia.
- Mechanism: Blocks serotonin transporter (SERT), increases synaptic 5-HT levels, improves mood/anxiety.
- Formulations: Tablets (5/10/20 mg), oral solution; brand name Lexapro.
Safety & Storage
GHS Symbol: GHS07 (Warning)
Hazard Statements: H302 (Harmful if swallowed), H312 (Harmful in contact with skin)
Storage: 2–8 °C, sealed, dry, away from light and moisture
Shelf Life: 24 months (proper storage)
