YANGONIN-Shandong Huashang Chemical Co., Ltd.

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YANGONIN

Brand：HS

Model：25kg/drum

Purity：99%

Cas：500-62-9

Createtime： 2026-04-14
Updatetime： 2026-04-15

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Product Details

useage	Industrial use
deliveryInfo
appearance	powder
Molecular Weight	258.27
aliasen
supplyCapacity	50000MT/Month
harbor	Qingdao,China
minorder	1KG
Appearance	Pale yellow to pale green crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: YANGONIN

Alias: 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one；4-Methoxy-6-(p-methoxystyryl)-2H-pyran-2-one；Kava lactone；MFCD00221733；PubChem: 5281575；ChEMBL: ChEMBL1098658

CAS No.: 500-62-9

EINECS No.: No public data

Molecular Formula: C??H??O?

Molecular Weight: 258.27 g/mol

Classification: Natural organic compound, kava lactone, plant extract, pharmaceutical intermediate, neuropharmacological reagent, research reagent, fine chemical

Physical & Chemical Properties

Appearance: Pale yellow to pale green crystalline powder, odorless; stable under normal conditions, incompatible with strong oxidizing agents; light-sensitive; slightly hygroscopic; may cause mild irritation upon contact with skin and eyes.

Density: 1.325 g/cm3 (25℃); refractive index n??/D 1.620 (predicted); LogP: 3.15 (predicted); PSA: 55.76; precise mass: 258.0841; UV absorption λmax: 218, 267, 357 nm.

Melting Point: 155-157℃ (lit.); decomposes at higher temperatures.

Boiling Point: 487.6±45.0℃ (predicted, atmospheric pressure); no obvious boiling phenomenon before decomposition.

Solubility: Slightly soluble in chloroform and methanol; soluble in ethanol, DMSO (5 mg/mL at 25℃) and DMF (5 mg/mL at 25℃); insoluble in water and non-polar solvents.

Flash Point: 177.4±22.2℃ (predicted); Vapor Pressure: 0.0±1.2 mmHg (25℃, predicted); pKa: Not available.

Purity: ≥98.0% (analytical grade, HPLC); ≥98.5% (natural extract grade); ≥99.0% (high-purity grade, for research use).

Storage Condition: Sealed, stored in a cool and dry place at 2-8℃, protected from light and moisture; keep container tightly closed; avoid high temperature, open flame and contact with oxidizing agents; for long-term storage, -20℃ freezer is recommended; avoid contact with skin and eyes.

Main Uses

Pharmaceutical & Pharmacological Research Field: As a key kava lactone from kava plant (Piper methysticum), it acts as a selective CB1 cannabinoid receptor agonist, MAO-B inhibitor and COX-II inhibitor; used for research on anxiety, pain relief, anti-inflammatory and neuroprotective effects.
Natural Product & Dietary Supplement Field: One of the six major active kava lactones, used as a raw material for dietary supplements with anxiolytic and sedative effects; note: potential hepatotoxicity, restricted in some regions.
Research & Laboratory Field: Used as a research reagent in molecular biology, pharmacology and natural product chemistry, mainly for the study of GABA receptor, cannabinoid receptor and monoamine oxidase-related signaling pathways; used as a reference substance for drug analysis and detection.
Other Fields: Exhibits antifungal and antimicrobial activities; used in the development and detection of pharmaceutical quality standards; applied in preclinical research of neuropsychiatric diseases and inflammatory disorders.

Specification Table

Item	Specification	Unit	Remarks
Product Name	YANGONIN	—	Alias: Kava lactone
CAS Number	500-62-9	—	Natural kava extract; potential hepatotoxicity
Molecular Formula	C??H??O?	—	Linear formula: 4-Methoxy-6-(p-methoxystyryl)-2H-pyran-2-one
Molecular Weight	258.27	g/mol
Appearance	Pale yellow to pale green crystalline powder	—	Odorless; light-sensitive; slightly hygroscopic
Melting Point	155-157	℃	lit. = literature value; decomposes at high temperature
Purity	≥98.0	%	Analytical grade; HPLC; natural product research