Pramipexole-Shandong Huashang Chemical Co., Ltd.

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Pramipexole

Brand：HS

Model：25kg/drum

Purity：99%

Cas：104632-26-0

Createtime： 2026-04-14
Updatetime： 2026-04-15

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Product Details

useage	Industrial use
deliveryInfo
appearance	powder
Molecular Weight	211.33
aliasen
supplyCapacity	50000MT/Month
harbor	Qingdao,China
minorder	1KG
Appearance	White to off-white crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: Pramipexole

Alias: (S)-Pramipexole; Pramipexole Base; 2-Amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole; U 98528E; MFCD00869076; RTECS No.: Not available; BRN: Not available; PubChem: 644007

CAS No.: 104632-26-0

EINECS No.: 600-593-1

Molecular Formula: C??H??N?S

Molecular Weight: 211.33 g/mol

Classification: Chiral compound, dopamine receptor agonist, pharmaceutical intermediate, API (Active Pharmaceutical Ingredient), fine chemical, neuropharmacological reagent, research reagent

Physical & Chemical Properties

Appearance: White to off-white crystalline powder, odorless; stable under normal conditions, incompatible with strong oxidizing agents and strong acids; slightly hygroscopic; irritant to eyes, respiratory system and skin.

Density: 1.17-1.20 g/cm3 (25℃, predicted); refractive index n??/D 1.583 (predicted); LogP: 1.42; PSA: 79.18; optical rotation (α)??/D -88.996° (c=0.005g/mL, methanol, 589nm); precise mass: 211.1143.

Melting Point: 288-290℃ (lit.); decomposes at higher temperatures.

Boiling Point: 378.0±42.0℃ (predicted, atmospheric pressure); no obvious boiling phenomenon before decomposition.

Solubility: Insoluble in water; freely soluble in DMSO (42 mg/mL at 25℃) and ethanol (42 mg/mL at 25℃); slightly soluble in methanol; insoluble in non-polar solvents such as benzene and chloroform.

Flash Point: 182.4±27.9℃ (predicted); Vapor Pressure: 0.0±0.9 mmHg (25℃, predicted); pKa: 9.47±0.20 (predicted).

Purity: ≥98.0% (analytical grade, HPLC); ≥98.5% (pharmaceutical grade); ≥99.0% (high-purity grade, for research use).

Storage Condition: Sealed, stored in a cool and dry place at 2-8℃, protected from light and moisture; keep container tightly closed; avoid high temperature, open flame and contact with oxidizing agents and strong acids; store in an inert atmosphere; for long-term storage, -20℃ freezer is recommended; avoid contact with skin and eyes.

Main Uses

Pharmaceutical & API Field: As a key API and dopamine receptor agonist, it is mainly used for the treatment of idiopathic Parkinson's disease (alleviating signs and symptoms) and moderate-to-severe primary restless legs syndrome (RLS); it can delay the decrease of dopamine content in the brain and improve motor function disorders.
Research & Laboratory Field: Used as a research reagent in molecular biology and pharmacology, mainly for the study of dopamine receptor-related signal pathways, neuropharmacological mechanisms, and the development of related drugs; used as a reference substance for drug analysis and detection.
Pharmaceutical Intermediate Field: Serves as an intermediate for the synthesis of Pramipexole derivatives and related drugs (such as Pramipexole Dihydrochloride, CAS: 104632-25-9), which is widely used in the research and production of antiparkinsonian drugs.
Other Fields: Used in the development and detection of pharmaceutical quality standards; applied in preclinical research of neuropsychiatric diseases, providing support for the research of dopamine-related disorders.

Specification Table

Item	Specification	Unit	Remarks
Product Name	Pramipexole	—	Alias: (S)-Pramipexole, Pramipexole Base
CAS Number	104632-26-0	—	TSCA listed; irritant to eyes and skin
Molecular Formula	C??H??N?S	—	Linear formula: C?H?N(CH?CH?CH?)C?H?N?S
Molecular Weight	211.33	g/mol
Appearance	White to off-white crystalline powder	—	Odorless; slightly hygroscopic; irritant
Melting Point	288-290	℃	lit. = literature value; decomposes at high temperature
Purity	≥99.0	%	High-purity grade; HPLC; for research use