Shandong Huashang Chemical Co., Ltd.
Product
(S)-(+)-Ketoprofen
  • Brand:HS
  • Model:25kg/drum
  • Purity:99%
  • Cas:22161-81-5
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance powder
Molecular Weight 254.28
aliasen
supplyCapacity 50000MT/Month
harbor Qingdao,China
minorder 1KG
Appearance White to off-white crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: (S)-(+)-Ketoprofen
Alias: Dexketoprofen; (S)-Ketoprofen; (S)-(+)-2-(3-Benzoylphenyl)propionic acid;  Benzeneacetic acid, 3-benzoyl-α-methyl-, (αS)-
CAS No.: 22161-81-5
EINECS No.: 606-944-5
Molecular Formula: C??H??O?
Molecular Weight: 254.28 g/mol
Classification: Pharmaceutical raw material, non-steroidal anti-inflammatory drug (NSAID), COX inhibitor, analgesic, antipyretic, fine chemical, pharmaceutical intermediate

Physical & Chemical Properties

Appearance: White to off-white odorless, non-hygroscopic fine or granular crystalline powder
Density: 1.198±0.06 g/cm3 (Predicted)
Melting Point: 75-78℃ (lit.)
Boiling Point: 431.3±28.0℃ (Predicted)
Solubility: Practically insoluble in water; ≥10.6 mg/mL in DMSO; ≥20.55 mg/mL in ethanol; freely soluble in chloroform, acetone and ether; soluble in benzene and strong alkali
Optical Rotation: (+49)°, 22℃/D, c=1 in methanol
Purity: ≥98.0% (HPLC), ≥99.0% (pharmaceutical grade), ≥98.5% (analytical grade)
Storage Condition: Sealed, room temperature, cool and dry place, protect from light; avoid high temperature, moisture and direct sunlight; keep container tightly closed

Main Uses

  • Pharmaceutical Field: Used as a non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic properties; it is an effective inhibitor of COX-1 and COX-2, with IC50 values of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2 respectively; used for the management of signs and symptoms of rheumatoid arthritis, osteoarthritis, pain and primary dysmenorrhea
  • Medical Research: Used as a biochemical reagent and standard substance for studying the mechanism of non-steroidal anti-inflammatory drugs, COX enzyme function and related signal pathways; used in the development, detection and efficacy evaluation of related drugs; applied in cell and animal experiments to explore anti-inflammatory, analgesic and antipyretic pharmacological effects
  • Other Fields: Used as a pharmaceutical intermediate for the synthesis of related anti-inflammatory and analgesic derivatives; used as an analytical standard for HPLC detection in pharmaceutical quality control; strictly prohibited for human use when used as a research reagent

Specification Table

Item
Specification
Unit
Remarks
Product Name
(S)-(+)-Ketoprofen

CAS Number
22161-81-5

Molecular Formula
C??H??O?

Molecular Weight
254.28
g/mol

Appearance
White to off-white crystalline powder
Odorless, non-hygroscopic
Purity
≥98.0
%
HPLC
Melting Point
75-78
lit. = literature value