4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3, 5 –dimethylbenzonitrile-Shandong Huashang Chemical Co., Ltd.

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4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3, 5 –dimethylbenzonitrile

Brand：HS

Model：25kg/drum

Purity：99%

Cas：269055-15-4

Createtime： 2026-04-14
Updatetime： 2026-04-15

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Product Details

useage	Industrial use
deliveryInfo
appearance	powder
Molecular Weight	435.28
aliasen
supplyCapacity	50000MT/Month
harbor	Qingdao,China
minorder	1KG
Appearance	White to off-white crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile

Alias: Etravirine; TMC 125; R 165335; Intelence; 4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethylbenzonitrile

CAS No.: 269055-15-4

EINECS No.: NA

Molecular Formula: C??H??BrN?O

Molecular Weight: 435.28 g/mol

Classification: Pharmaceutical raw material, HIV reverse transcriptase inhibitor, antiviral drug, fine chemical, pharmaceutical intermediate

Physical & Chemical Properties

Appearance: White to off-white crystalline powder, odorless

Density: 1.56 g/cm3

Melting Point: 248-252℃

Solubility: Slightly soluble in water; soluble in DMSO, ethanol and methanol; insoluble in non-polar solvents

Purity: ≥98.0% (HPLC), ≥95.0% (AR grade)

Storage Condition: Sealed, cool and dry place, protect from light; avoid high temperature, moisture and direct sunlight; keep container tightly closed

Main Uses

Pharmaceutical Field: Used as a novel HIV reverse transcriptase inhibitor, mainly used in the treatment of HIV infection; effective for HIV strains resistant to other reverse transcriptase inhibitors
Medical Research: Used as a biochemical reagent and standard substance for studying HIV replication mechanism and antiviral drug research; used in the development and detection of antiviral drugs
Other Fields: Used as a pharmaceutical intermediate for the synthesis of related antiviral derivatives; applied in laboratory research on antiviral drug screening and efficacy evaluation

Specification Table

Item	Specification	Unit	Remarks
Product Name	4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile	—
CAS Number	269055-15-4	—
Molecular Formula	C??H??BrN?O	—
Molecular Weight	435.28	g/mol
Appearance	White to off-white crystalline powder	—
Purity	≥98.0	%	HPLC
Melting Point	248-252	℃