Moxidectin-Shandong Huashang Chemical Co., Ltd.

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Moxidectin

Brand：HS

Model：25kg/drum

Purity：99%

Cas：113507-06-5

Createtime： 2026-04-14
Updatetime： 2026-04-15

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Product Details

useage	Industrial use
deliveryInfo
appearance	powder
Molecular Weight	639.82
aliasen
supplyCapacity	50000MT/Month
harbor	Qingdao,China
minorder	1KG
Appearance	White to off-white amorphous or crystalline solid powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: Moxidectin; Alias: Moxydectin, Moxidectina, Moxidectine, Milbemycin B monoxime derivative, MXD

CAS Number: 113507-06-5 (MDL: MFCD00868547; EINECS: 635-129-7)

Molecular Formula: C??H??NO?

Molecular Weight: 639.82 g/mol

Structural Formula: (6R,25R)-5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6-methylene-milbemycin A3 monoxime (a macrolide antibiotic, derived from the fermentation product of Streptomyces hygroscopicus subsp. aurescens, a semi-synthetic derivative of nemadectin with macrolide ring functional groups)

Classification: Macrolide antibiotic, antiparasitic drug, veterinary drug raw material, pharmaceutical intermediate, small molecule inhibitor, medical raw material, antiparasitic veterinary drug

Physical & Chemical Properties

Moxidectin is a white to off-white amorphous or crystalline solid powder, odorless, tasteless, and practically insoluble in water; very soluble in ethanol (96%), soluble in dimethyl sulfoxide (DMSO), slightly soluble in n-hexane, and soluble in moderate heating and ultrasonic conditions in water. Its pKa value is 12.46±0.70 (predicted), showing weak basicity. It is stable under normal temperature and pressure, but is sensitive to heat, moisture and light—long-term exposure to high temperature (above 150°C) or humidity may cause decomposition, and light exposure may lead to reduced activity. Its density is 1.23±0.1 g/cm3 (25°C, predicted), boiling point is 790.0±70.0°C at 760 mmHg (predicted), melting point is 132°C, and vapor pressure is <0.0001 mmHg at 25°C with a LogP of 5.2 at 20°C. It has no obvious hygroscopicity, but it is easy to decompose when in contact with moisture for a long time, so it needs to be stored in a dry and low-temperature environment.

Key physical and chemical parameters are detailed in the specification table below, meeting the requirements of high-purity pharmaceutical grade (USP/ChP), veterinary pharmaceutical grade and research grade.

Main Uses

Moxidectin is a second-generation derivative of the milbemycin family, a broad-spectrum antiparasitic drug developed by Novartis Animal Health. It has strong killing and repellent effects on internal and external parasites, and is widely used in veterinary medicine and human medicine, as well as related research fields:

Veterinary Pharmaceutical Industry: Used as a raw material for antiparasitic drugs, mainly used for the treatment and prevention of internal nematodes and external parasites in animals such as cattle, sheep, horses, dogs, cats and pigs. It is clinically used to treat cow internal nematodes and external parasites such as lice, flies and maggots, as well as pig sarcoptic mange, and can also prevent and control filarial and intestinal helminth infections in animals. It can be made into pour-on solutions, injections, tablets, powders and other preparations for oral, topical or injection administration.
Veterinary Preparation Production: Key raw material for the synthesis of moxidectin veterinary preparations (such as 0.5% moxidectin pour-on solution), with various specifications to meet the needs of different animal varieties and feeding scenarios. It is used to produce high-purity veterinary formulations that meet international pharmacopoeia standards (USP/ChP), ensuring drug efficacy and safety for animal use.
Human Pharmaceutical Industry: Used as a raw material for antiparasitic drugs, approved by the FDA for the treatment of onchocerciasis (river blindness) in humans, and included in the World Health Organization (WHO) essential medicines list, playing an important role in global public health.
Biological & Pharmaceutical Research: Used as a research reagent in microbiology, pharmacology and parasitology experiments, including parasite sensitivity testing, research on the antiparasitic mechanism of macrolide drugs, and in vitro drug screening for parasitic diseases. It is also used in preclinical research on new antiparasitic drugs and evaluation of drug safety and efficacy.

Packaging & Storage

Packaging Method

Lab/Research Grade: 10mg, 1g, 5g, 10g sealed glass bottles or aluminum foil bags (filled with inert gas); 100g, 500g HDPE plastic bottles with PTFE liners, suitable for laboratory research and small-batch testing.

Pharmaceutical Grade & Veterinary Pharmaceutical Grade: 100g, 500g, 1kg sealed glass bottles (filled with nitrogen); 1kg aluminum foil bags, 5kg, 25kg cardboard drums or galvanized iron drums with PTFE liners and nitrogen-sealed; customized packaging available per customer requirements (such as 10ml, 20ml vials for injection-grade preparations), complying with GMP standards for pharmaceutical raw materials and veterinary drug specifications.

Storage Method

Store in a cool, dry, dark, and well-ventilated warehouse at a temperature of -20°C (freezer storage recommended). Keep containers tightly sealed and protected from light to prevent moisture absorption, oxidation and decomposition, and avoid reduction of drug activity. Avoid contact with water, strong oxidants, strong acids and strong bases; keep away from fire, heat sources, and direct sunlight. The prepared preparations should be used within the validity period, and the opened preparations should be used up within 10 weeks. It is sensitive to moisture, light and temperature, so strict moisture-proof, anti-light and low-temperature measures must be taken. Shelf life is 24 months under standard sealed, low-temperature, and dry storage conditions (complying with GMP storage requirements for pharmaceutical and veterinary drugs).

Comprehensive Specification Table

Item	Specification	Unit	Remarks
Product Name	Moxidectin	—	Alias: Moxydectin, MXD; Milbemycin family derivative
CAS Number	113507-06-5	—	MDL: MFCD00868547; EINECS: 635-129-7; PubChem: 6440
Molecular Formula	C??H??NO?	—	Macrolide antibiotic; derived from Streptomyces fermentation product
Molecular Weight	639.82	g/mol	Theoretical calculation value; consistent with USP/ChP standards
Appearance	White to off-white amorphous or crystalline solid powder	—	Odorless, tasteless; non-hygroscopic; stable under normal conditions
Purity	≥99.0 (Pharmaceutical Grade); ≥98.0 (Research Grade); ≥97.0 (Veterinary Pharmaceutical Grade)	%	Meets USP/ChP standards; 92.0% to 102.0% content range; ≤1.3% water content
Melting Point	132	℃	Literature value; stable at room temperature; consistent with standard specifications
Boiling Point	790.0±70.0 (760 mmHg)	℃	Predicted value; decomposes before complete boiling
Solubility	Practically insoluble in water; very soluble in ethanol; soluble in DMSO	—	Slightly soluble in n-hexane; soluble in water under moderate heating and ultrasonic
Density	1.23±0.1 (25°C)	g/cm3	Predicted value at room temperature; solid state
Main Impurities	≤0.3 (Pharmaceutical Grade); ≤1.0 (Research Grade); ≤2.0 (Veterinary Pharmaceutical Grade)	%	Including moisture, fermentation intermediates, degradation products and heavy metals (≤10ppm); ≤0.2% ignition residue
Main Uses	Antiparasitic drug, pharmaceutical raw material, veterinary drug raw material, research reagent	—	Treatment of onchocerciasis; animal internal and external parasite control; pharmaceutical research
Packaging Method	10mg-1kg bottles/bags; 1kg aluminum foil bags; 5kg-25kg cardboard drum/iron drum	—	GMP compliant; sealed, moisture-proof, light-proof; filled with inert gas or nitrogen
Storage Method	-20°C, cool, dry, dark, sealed; away from moisture/oxidants/acids/bases; avoid light	—	Shelf life 24 months; GMP storage; opened preparations used up within 10 weeks