Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: Difluoroacetic acid
CAS Number: 381-73-7
Molecular Formula: C?H?F?O?
Molecular Weight: 96.04 g/mol
Synonyms: 2,2-Difluoroacetic acid; α,α-Difluoroacetic acid
Classification: Fluorinated carboxylic acid, fine chemical raw material, pharmaceutical intermediate, pesticide intermediate, organic synthesis reagent
Physical & Chemical Properties
Appearance: Colorless transparent volatile liquid; strong pungent acidic odor
Melting Point: -1 °C
Boiling Point: 132–134 °C
Density: 1.526 g/cm3 (20 °C)
Refractive Index: 1.345
Flash Point: 78 °C
Solubility: Miscible with water, ethanol, methanol, ether and most organic solvents; good compatibility with polar solvents
Stability: Stable under normal sealed storage; corrosive; volatile; avoid high temperature, strong oxidants and strong bases; easy to form salt with alkali substances; corrosive to metal and skin
Key Parameters: Purity ≥99.0%; Moisture ≤0.2%; Boiling point range 132–134 °C
Uses
Difluoroacetic acid is an important fluorinated fine chemical intermediate.
It is widely used in pharmaceutical synthesis for introducing difluoromethyl group, applied in the preparation of anti-viral, anti-inflammatory and anti-tumor drug intermediates.
In agrochemical industry, it is used for synthesizing high-efficiency herbicides, fungicides and pesticide intermediates containing difluoro structure.
It serves as catalyst and chemical reagent in organic synthesis, also used as raw material for fluorinated fine chemicals and chemical analysis reagents.
Packaging & Storage
Packaging
Laboratory grade: 100ml, 500ml sealed brown glass bottles
Industrial grade: 25kg, 50kg lined plastic drum or anticorrosive iron drum
Storage: Store in cool, dry, dark and well ventilated place; keep tightly sealed, away from heat source and flame; strictly avoid contact with strong alkali, oxidants and metals; prevent volatile leakage
Shelf Life: 24 months under standard sealed cool storage
Transportation: Belongs to corrosive chemical; transport away from fire, heat and alkaline goods; keep sealed to prevent leakage and volatile gas emission
Comprehensive Specification Table
