Shandong Huashang Chemical Co., Ltd.
Product
5-Bromo-2-fluorophenylacetic acid
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:883514-21-4
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance powder
Storage Sealed container at 2–8 ℃, cool dry place, avoid strong alkali, direct sunlight and high temperature
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Soluble in methanol, ethanol, acetone, DMSO
harbor Qingdao,China
minorder 1KG
Melting Point 111–112 ℃
Batch NO.:FBA-883514-0605
Assay(HPLC):99.32%
Loss on Drying:0.15%
Residue on Ignition:<0.07%
Single Individual Impurity:≤0.08%
Total Related Substances:≤0.28%
Heavy Metal(Pb,As,Cd):<10ppm
Residual Organic Solvents:Compliant with ICH Q3C specification


Product Usage

This fluorinated brominated phenyl acetic acid is high-value fine pharmaceutical intermediate, not applicable for food, feed and cosmetic raw material production. It is mainly adopted as core building block for small-molecule drug synthesis including kinase inhibitor, CNS therapeutic agents and anti-inflammatory API intermediates in pharmaceutical R&D and production factories. The terminal carboxylic acid group can undergo esterification, amide condensation and decarboxylation reactions; ortho-fluorine and para-bromine substituents on benzene ring support further Suzuki coupling, nucleophilic aromatic substitution to construct complex heterocyclic and aromatic drug skeletons. High purity grade is widely used in laboratory custom synthesis for new drug candidate screening and medicinal chemistry research projects. It also serves as key starting raw material for synthesizing agrochemical bactericide intermediates with fluorine-bromine substituted aromatic structure; tiny batches are supplied as analytical reference standard for pharmaceutical impurity testing labs. No coating, adhesive or daily chemical formulation application exists for this substance.

Safety Information

GHS Warning-grade irritant with hazard statements H315(skin irritation), H319(serious eye damage), H335(may cause respiratory tract irritation from dust inhalation). Operators must wear nitrile gloves, full-face protective goggles and dustproof lab coat; all weighing and feeding operations should be completed inside chemical fume hood to prevent dust inhalation and skin contact. Upon skin contact, continuously rinse contaminated skin with abundant soapy running water over 15 minutes; if splashed into eyes, uninterrupted flush with clean water no less than 15 min and go to ophthalmic treatment immediately. Accidental oral intake triggers stomach ache, nausea and throat irritation; massive ingestion needs prompt symptomatic hospital treatment. Discarded crystalline waste and contaminated filter scraps belong to pharmaceutical hazardous waste, deliver to licensed hazardous waste processor per local environmental law, strictly forbidden to discharge into sewer or domestic garbage. Store separately from strong bases, strong oxidants and reactive reducing agents to avoid exothermic decomposition reaction.