Batch NO.:API-63990-0605 Assay(HPLC):99.26% Loss on Drying:0.21% Residue on Ignition:<0.08% Single Unknown Impurity:≤0.10% Total Related Substances:≤0.30% Heavy Metals(Pb):<10ppm, As<2ppm Residual Organic Solvents:Meet ICH Q3C limit standards

This piperazine substituted acetophenone dihydrochloride is exclusive high-end pharmaceutical intermediate, prohibited for food, feed and cosmetic raw material usage. It serves as core synthetic precursor for multiple cardiovascular and anti-arrhythmia APIs, mainly applied for manufacturing selective adrenergic receptor antagonist drugs in fine pharmaceutical factories. During drug synthesis process, the ketone group on benzene ring and side-chain hydroxyl/piperazine amine group participate in condensation, reduction and alkylation cascade reactions to construct finished drug molecular skeleton. High purity pharmaceutical grade is widely used in custom lab synthesis for new generation β-blocker candidate medicines in pharmaceutical R&D institutes. Besides bulk API intermediate supply, small lab batches are adopted for pharmacology research raw material for new drug screening projects; it also works as reference standard substance for pharmaceutical impurity analysis and HPLC qualitative/quantitative detection in drug testing laboratories. No industrial coating or pesticide formulation application for this compound.

GHS Warning classification with hazard codes H315(Skin irritation), H318(Severe eye damage), H335(May cause respiratory irritation from dust inhalation). Operators must equip nitrile resistant gloves, full-face safety goggles and dust-proof lab coat during feeding, sampling and weighing inside fume hood to prevent dust exposure and skin/mucosa contact. For skin contamination, wash affected area with plenty of soapy running water continuously over 15 minutes; once splashed into eyes, perform uninterrupted clean water irrigation more than 15 min and seek immediate professional ophthalmic treatment. Accidental oral ingestion causes stomach discomfort, nausea and abdominal pain; large-dose intake requires urgent hospital symptomatic therapy. All waste crystalline residues and polluted filter materials are categorized as pharmaceutical hazardous waste, delivered to qualified certified waste disposal enterprise per local environmental protection regulations, strictly forbidden to drain into domestic sewage or ordinary garbage. Store separately from concentrated alkali, strong oxidants and strong reducing agents to avoid exothermic neutralization and decomposition reactions.