Loratadine ketone-Shandong Huashang Chemical Co., Ltd.

Product

Current Position： Home > Product >Pharmaceutical Chemicals >Loratadine ketone

Loratadine ketone

Brand：HuaShang

Model：25kg/drum

Purity：99%

Cas：130642-50-1

Createtime： 2026-04-14
Updatetime： 2026-04-15

Send Message

Product Details

useage	Industrial use
deliveryInfo
appearance	powder
Storage Condition	Sealed container, 2–8 ℃ under dry environment, avoid direct sunlight and humid atmosphere
aliasen
supplyCapacity	50000Metric Ton/Month
Solubility	Practically insoluble in water; soluble in methanol, ethanol, DMSO, DCM, acetonitrile; sparingly soluble in hexane
harbor	Qingdao,China
minorder	1KG
Melting Point	179–186 °C

Assay (HPLC):99.12%
Loss on Drying:0.18%
Residue on Ignition:＜0.05%
Heavy Metal (Pb):＜10 ppm
Arsenic:＜2 ppm
Single Unknown Impurity:≤0.10%
Total Related Impurities:≤0.32%
Residual Organic Solvents: Compliant with ICH Q3C requirements

Product Application

Pharmaceutical Reference Standard & Impurity Marker: Official impurity reference substance for Loratadine/Desloratadine (second-generation antihistamine API), used for HPLC/GC qualitative & quantitative impurity testing in pharmaceutical QC laboratory, complying with EP/USP pharmacopoeia inspection standard.
Pharmaceutical Intermediate: Key synthetic intermediate during loratadine bulk drug manufacturing process for anti-allergy raw material synthesis.
Preclinical Research Reagent: Applied for antihistamine pharmacological screening experiment, H1 receptor binding assay in drug discovery lab.

Safety & GHS Information

GHS Hazard Level: Warning

Hazard Statements:

H315: Causes skin irritation

H319: Causes serious eye irritation

H335: May cause respiratory irritation when inhaled as fine dust

Operation Guide: Wear nitrile gloves, splash-proof safety goggles and lab coat during sampling and weighing; avoid dust inhalation and skin direct contact.

First Aid: Rinse contaminated skin/eyes with abundant running clean water for ≥15 minutes; seek professional medical help for persistent discomfort.

Waste Disposal: Classified as pharmaceutical hazardous organic waste, delivered to certified hazardous waste disposal institute per local environmental legislation, prohibited to drain directly into sewer.