1.Assay:98.56%(HPLC) 2.Loss on Drying:0.22% 3.Residue on Ignition:0.06% 4.Heavy Metal(Pb):<10ppm 5.Arsenic:<2ppm 6.Single Unknown Impurity:≤0.15% 7.Total Related Impurity:≤0.40% 8.Residual Organic Solvent: Complies with ICH Q3C specification

Bretazenil is a novel partial agonist of benzodiazepine/GABA? receptor, exclusively applied for preclinical pharmaceutical research and laboratory reference standard, prohibited for human clinical medication and illegal recreational use globally. 1.Pharmacology experiment: It selectively modulates GABA? receptor subtypes, used in in-vitro cell binding assay and animal model tests for anxiolytic, anticonvulsant and sedative research; inhibits pentylenetetrazol-induced convulsion and shows anti-anxiety activity in mouse elevated plus maze test. 2.Analytical reference standard: Used as HPLC/GC calibration reference substance for quantitative detection of benzodiazepine derivatives in pharmaceutical R&D labs and forensic testing labs. 3.Medicinal chemistry intermediate: Serves as parent skeleton for structural modification to develop new subtype-selective benzodiazepine lead compounds for central nervous system drug screening.

GHS Hazard Class: Warning; Hazard Codes: H302(Harmful if swallowed), H315(Skin irritation), H319(Serious eye damage), H335(May cause respiratory irritation). Operational requirement: Wear nitrile gloves, dust-proof goggles and full-body lab coat during weighing and dispensing to avoid dust inhalation and skin contact. Waste disposal: Residual solid and waste solvent belong to controlled hazardous chemical waste, delivered to certified hazardous waste treatment institute per local environmental regulation. First-aid: Rinse contaminated eyes/skin with plenty of running water for minimum 15 minutes; induce no vomiting after accidental oral intake and seek immediate medical help. Regulatory note: Classified as controlled psychotropic research raw material in most regions, subject to strict purchase & usage record management per drug control laws.