Shandong Huashang Chemical Co., Ltd.
Product
Carbamic acid, (2-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, cis- (9CI)
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:155837-16-4
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
Boiling Point 320.8±31.0 °C
useage Industrial use
deliveryInfo
appearance powder
Stability Stable under ambient conditions; avoid strong acids, strong bases, and excessive heat
Storage 2–8°C, sealed, dry, protected from light
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Soluble in methanol, ethanol, dichloromethane, ethyl acetate; slightly soluble in water
harbor Qingdao,China
minorder 1KG
Melting Point 78–82 °C
  • Appearance: White crystalline solid
  • Purity (HPLC): ≥98.0%
  • Moisture: ≤0.3%
  • Residue on Ignition: ≤0.1%
  • Single Impurity: ≤0.5%
  • Heavy Metals (as Pb): ≤10 ppm


Applications

This compound is a chiral cyclic amino alcohol building block with a Boc-protected amine, widely used in pharmaceutical synthesis. The cis-1,2-substituted cyclopentane core serves as a key scaffold for GPCR ligands, kinase inhibitors, and CNS drug candidates. The Boc group enables orthogonal amine protection/deprotection, while the hydroxyl group allows further derivatization (esterification, etherification). It is also utilized in asymmetric synthesis and chiral library construction for SAR studies.

Safety Information

GHS Classification: H315 (Causes skin irritation), H319 (Causes serious eye irritation)
Signal Word: Warning
Risk Codes: R36/38
Safety Codes: S26; S36
Acute toxicity data is limited; however, it is considered to have low acute toxicity. Skin contact may cause redness, itching, and mild dermatitis; rinse with plenty of water. Eye contact can lead to irritation, tearing, and conjunctivitis; flush with clean water for at least 15 minutes and seek medical attention if needed. Inhalation of dust may cause mild respiratory irritation. Use in a well-ventilated area; wear nitrile gloves and safety goggles during handling. Store separately from food, feed, and strong acids. Dispose of waste per local regulations.