Shandong Huashang Chemical Co., Ltd.
Product
N-Methyl-4-phenyl-4-piperidinamine
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:182621-56-3
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
Boiling Point 328.4 °C
useage Industrial use
deliveryInfo
appearance powder
Storage Sealed, 2–8 °C, away from light and moisture
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Soluble in methanol, ethanol, DMSO; slightly soluble in water
harbor Qingdao,China
minorder 1KG
Melting Point 88–90 °C
  1. Appearance: White crystalline powder
  2. Purity (HPLC): ≥98.0% (typically ≥98.5%)
  3. Moisture: ≤0.3%
  4. Melting Point: 88–90 °C
  5. Total Impurities: ≤1.0%


Application

This compound is a key pharmaceutical intermediate with a rigid piperidine ring, widely used in:
  • Central nervous system (CNS) drug synthesis: Precursor for antidepressants, antipsychotics, and analgesics; its 4-phenyl-4-methylamino piperidine scaffold is critical for modulating neurotransmitter receptors.
  • Opioid receptor modulators: Intermediate for developing selective opioid ligands, targeting pain management and addiction treatment.
  • Organic synthesis: Building block for complex nitrogen-containing heterocyclic compounds, especially in the preparation of bioactive molecules and pharmaceutical candidates.

Safety Information

GHS Classification: Warning
Hazard Statements: H302 (Harmful if swallowed); H315 (Causes skin irritation); H319 (Causes serious eye irritation); H335 (May cause respiratory irritation)
  • Acute toxicity: Oral LD50 (rat) >1500 mg/kg (slightly toxic).
  • Skin/eye irritation: Moderate irritant; may cause redness, itching, or conjunctival damage.
  • Inhalation: Dust may irritate the respiratory tract, causing cough or discomfort.
  • Handling: Use in a fume hood; wear nitrile gloves, chemical goggles, and a dust mask.
  • Storage: Keep away from strong acids, oxidants, and food; store in a cool, dry place.
  • First aid: Rinse skin with soapy water; flush eyes with water for 15 min; seek medical help if swallowed or inhaled.