Shandong Huashang Chemical Co., Ltd.
Product
4,4-dimethyl-1-(trimethylsilyl)pentane-1,3-dione
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:286854-89-5
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance Colorless to pale yellow clear liquid
Storage Sealed, dry, 2-8°C, away from strong oxidants
aliasen
supplyCapacity 50000Metric Ton/Month
harbor Qingdao,China
minorder 1KG
  1. Appearance: Colorless to pale yellow clear liquid
  2. Purity (GC): ≥95.0%
  3. Moisture: ≤0.2%
  4. Boiling Range: 220–225 °C
  5. Refractive Index: 1.430–1.435 (20 °C)
  6. Density: 0.960–0.970 g/mL (25 °C)


Application

4,4-Dimethyl-1-(trimethylsilyl)pentane-1,3-dione is a key silylated β-diketone intermediate widely used in organic synthesis, pharmaceutical manufacturing, and material science. As a versatile building block, it is primarily utilized for the introduction of trimethylsilyl (TMS) protecting groups in complex molecule synthesis, especially in the production of specialty pharmaceuticals and natural product derivatives. Its β-diketone structure enables efficient chelation with metal ions, making it a valuable ligand in coordination chemistry and catalyst preparation. In agrochemicals, it serves as an intermediate for synthesizing high-value herbicides and fungicides with enhanced stability and bioavailability. Additionally, it is applied in the synthesis of functional silicone materials and liquid crystal compounds, leveraging the unique properties of silicon-oxygen bonds. Its high chemical stability and selective reactivity make it an essential reagent for fine chemical synthesis and advanced material development.

Safety Information 

GHS07 (Warning): Skin irritant; eye irritant; may cause respiratory irritation.
  • Routes of Entry: Inhalation, ingestion, skin/eye contact
  • Acute Toxicity: Oral LD50 (rat) >2,000 mg/kg (Category 5); low dermal toxicity
  • Skin Contact: Causes mild irritation, redness, itching; prolonged contact may cause dryness
  • Eye Contact: Irritating; may cause redness, tearing; rinse with plenty of water for 15 minutes and seek medical attention
  • Inhalation: Vapor may irritate respiratory tract, causing cough; use in well-ventilated areas with masks
  • Ingestion: May cause nausea, vomiting; do not induce vomiting, rinse mouth and seek medical advice
  • Precautions: Wear protective gloves, goggles, and lab coat; avoid breathing vapor
  • Storage: Keep tightly closed in a cool, dry place; separate from oxidants
  • Transport: Not classified as dangerous goods; UN 3082, Class 9, Packing Group III