88021-73-2 is a highly enantioselective chiral reducing agent used in asymmetric synthesis and pharmaceutical intermediate manufacturing. It is a proprietary analog of (?)-DIP?Chloride, designed for improved stability and stereoselectivity in industrial processes. It reduces prochiral ketones (aromatic, α,β?unsaturated, cyclic) to chiral secondary alcohols with ee >95%, a critical step in producing single?enantiomer drugs (antivirals, analgesics, antihypertensives). It is also used for chiral center construction in complex natural products and fine chemicals. Its high solubility in nonpolar solvents and tolerance for low?temperature reactions (?78 °C) ensure high yields and stereopurity. In academic research, it serves as a tool to study chiral induction mechanisms. Due to its proprietary nature, it is supplied only to qualified industrial and research clients under controlled conditions.
GHS classification: Flam. Liq. 2, Skin Corr. 1B, Eye Dam. 1, Asp. Tox. 1, STOT SE 3, Repr. 2, Aquatic Chronic 2. Signal word: Danger.
