It is an important dihalogenated pyrimidine intermediate with two reactive chlorine atoms. It readily participates in nucleophilic substitution, cross-coupling and cyclization reactions to build diverse heterocyclic structures. It is widely used for synthesizing antitumor, antibacterial and antiviral drugs, which can optimize molecular structure and enhance pharmaceutical activity. In agrochemical field, it serves as key raw material for fungicides, herbicides and insecticides. Additionally, it is applied to produce biochemical reagents and fine chemical derivatives. This compound plays an essential role in new drug screening, pesticide development and organic synthesis research.
This solid chemical has slight toxicity and obvious irritation. Inhalation of dust will irritate respiratory tract and cause throat pain or cough. Conduct operations in ventilated areas and wear dust masks and protective gloves. Skin contact may result in redness and itching, while eye contact will cause severe stinging and mucosal damage. Rinse thoroughly with plenty of running water for over 15 minutes once exposed. Thermal decomposition releases toxic chloride gas. Keep away from open flame, high temperature and oxidizing substances. Do not store together with food. All waste shall be handled as hazardous waste to prevent personal harm and environmental contamination.