N-METHYL-2-(TRIFLUOROMETHOXY)ANILINE
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| Boiling Point |
185–190 °C
|
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
Colorless to pale yellow liquid
|
| Stability |
Stable under normal conditions; avoid strong acids/oxidants
|
| aliasen |
|
| supplyCapacity |
50000Metric Ton/Month
|
| Solubility |
Slightly soluble in water, soluble in organic solvents
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
- Appearance: Colorless to pale yellow clear liquid
- GC Purity: ≥98.0%
- Moisture: ≤0.2%
- Refractive Index: 1.460–1.465
- Relative Density: 1.22–1.24
- Residue on Evaporation: ≤0.1%
- Free Amine: ≤0.3%
Applications
N-Methyl-2-(trifluoromethoxy)aniline is a fluorinated aromatic intermediate with high synthetic value. It is widely used in pharmaceutical R&D for synthesizing kinase inhibitors, anti-inflammatory and analgesic drugs. Its trifluoromethoxy group enhances metabolic stability and bioavailability in drug molecules. Applied in agrochemicals for making herbicide and fungicide intermediates. Used in organic synthesis for constructing complex heterocyclic compounds via coupling reactions (Suzuki, Buchwald). Also serves as a key raw material for fluorinated dyes and functional materials.
Safety Information
Irritant & harmful if swallowed/inhaled.
- Inhalation: Vapor irritates respiratory tract; use ventilation and respirator.
- Skin Contact: Causes irritation; wear gloves, wash skin promptly.
- Eye Contact: Causes severe irritation; flush with water for 15+ minutes.
- Ingestion: Harmful; may cause nausea, vomiting.
- Storage: Keep away from heat, sparks, oxidants; store separately from food.
- Disposal: Treat as hazardous chemical waste.
