1. Appearance: White crystalline powder
2. HPLC Purity: ≥98.0%
3. Moisture: ≤0.5%
4. Melting Point: 210-215 °C (dec.)
5. Heavy Metal (Pb): ≤10 ppm
6. Residue on Ignition: ≤0.2%
7. Purity (Titration): 98.0-102.0%

Applications

• PXR Inhibitor: Potent and selective inverse agonist/antagonist of pregnane X receptor (PXR), a critical regulator of drug metabolism; used to study drug-drug interactions and enhance therapeutic efficacy of co-administered drugs。
• Antitumor Agent Precursor: Serves as a core fragment for synthesizing anticancer compounds targeting FAK and Wnt/β-catenin pathways, inhibiting tumor cell proliferation and metastasis。
• Chemical Intermediate: Building block for triazole-based drug development, especially in oncology and anti-inflammatory research。

Safety Information

• Toxicity: Low acute toxicity; no severe toxicity data reported.
• Inhalation: May cause mild respiratory irritation (H335); use ventilation and dust masks。
• Skin Contact: May cause skin irritation (H315); wear protective gloves, rinse with soap and water after contact。
• Eye Contact: May cause serious eye irritation (H319); flush with water for 15 minutes, seek medical attention if irritation persists。
• Ingestion: Large doses may cause gastrointestinal discomfort; no severe toxicity expected.
• Storage: Keep tightly closed, away from oxidants and strong acids; store in cool, dry place.
• Disposal: Follow local regulations for hazardous waste disposal.