Shandong Huashang Chemical Co., Ltd.
Product
4-Fluorobenzoyl chloride
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:403-43-0
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
Boiling Point 182-184 °C
useage Industrial use
deliveryInfo
appearance Colorless transparent liquid
Storage Condition Sealed cool storage, isolated from moisture, alkali and oxidants
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Reacts with water, soluble in ether, benzene and other organic solvents
harbor Qingdao,China
minorder 1KG

  1. Appearance: Colorless clear liquid
  2. Purity (GC): ≥99.0%
  3. Moisture: ≤0.1%
  4. Free Acid: ≤0.2%
  5. Distillation Range: 182-184 °C
  6. Heavy Metal (Pb): ≤5 ppm
  7. Total Impurities: ≤1.0%


Applications

4-Fluorobenzoyl chloride is a vital fluorinated aromatic acyl chloride intermediate with high chemical activity. Its active acyl chloride group can easily participate in acylation, esterification, amidation and condensation reactions to synthesize various fluorine-containing fine chemicals. In pharmaceutical industry, it is widely used to prepare antibacterial, anti-inflammatory, analgesic and central nervous system drugs, and serves as core building block for developing anti-tumor and cardiovascular pharmaceutical intermediates. The introduced fluorine atom can effectively improve drug metabolic stability, lipophilicity and biological activity, greatly enhance curative effect and reduce side effects. In agrochemical field, it is applied to synthesize high-efficiency low-toxicity pesticides, fungicides and herbicides to optimize pesticide molecular structure and promote insecticidal and bactericidal performance. Besides, it is commonly used in manufacturing liquid crystal materials, organic dyes, fluorescent agents and polymer additives. It is also frequently adopted in laboratory organic synthesis and new reaction route research. With stable chemical property and strong reaction versatility, this product occupies an important position in fluorine chemical industry, and has stable demand and broad development prospect in medicine, pesticide and new material fields.

Safety Information

This substance is corrosive and irritant hazardous chemical with strong stimulation to human tissues. Inhalation of its volatile steam will severely irritate respiratory tract and nasal mucosa, cause sore throat, cough, chest distress and even respiratory inflammation, so all operations must be done in well ventilated place with gas mask. Direct skin contact will lead to obvious corrosion and burning pain, easily cause skin redness, blistering and tissue damage, operators must wear acid-proof gloves and protective clothes, and flush contaminated skin with plenty of clean water immediately. Once splashed into eyes, it will cause severe conjunctival corrosion and corneal injury, instantly rinse eyes with running water for more than fifteen minutes and seek medical treatment urgently. Accidental ingestion will strongly erode oral cavity and digestive tract, induce nausea, vomiting and abdominal pain, timely take medical treatment. It reacts violently with water and alkaline substances to release harmful irritant gas, and easy to produce toxic fumes under high temperature decomposition. Keep far away from fire source during storage. All waste materials shall be disposed strictly in accordance with dangerous chemical waste regulations to avoid personal injury and environmental pollution.