TATU is a high-efficiency uronium-type peptide coupling reagent widely applied in organic synthesis and biopharmaceutical research. It can rapidly activate carboxylic acid groups to form active intermediates, efficiently promote amide bond formation and peptide chain condensation reaction with low racemization rate and few side reactions. It is perfectly suitable for solid-phase peptide synthesis, liquid-phase fragment splicing and cyclic peptide preparation, and widely used in the production of polypeptide drugs, amino acid derivatives and various amide fine chemicals. Compared with traditional condensation agents, it features mild reaction conditions, high coupling efficiency and easy post-treatment, which can effectively improve product yield and final product purity. In addition, it is commonly used for molecular modification of proteins, polysaccharides and biological macromolecules, as well as structural optimization of pesticide intermediates and medical diagnostic reagents. It has become one of the mainstream core condensation reagents in peptide chemistry, new drug development and laboratory organic synthesis, and holds stable application demand and important research value in the global fine chemical market.

This product is classified as mild irritant and sensitizing chemical with certain biological stimulation. Inhalation of fine dust will cause discomfort and irritation to nasal cavity and respiratory tract, leading to cough and throat pain, so operators must wear dust-proof masks and keep sufficient ventilation during operation. Direct long-term skin contact may trigger local redness, itching and allergic skin inflammation, staff need to wear complete nitrile protective gloves and protective clothing, and clean the contacted skin thoroughly with soap and flowing water after operation. Once the powder enters eyes accidentally, it will cause severe stinging and conjunctival irritation, immediately flush eyes with plenty of running clean water for more than fifteen minutes and seek professional medical treatment in time. Accidental ingestion will induce nausea, stomach distension and other gastrointestinal adverse reactions, do not induce vomiting arbitrarily and take medical measures promptly. The product is stable under low temperature dry environment, easy to decompose and lose activity when exposed to high temperature, humidity, strong acid and strong alkali. Keep away from strong oxidants during storage. All waste materials shall be disposed in accordance with local hazardous waste management rules to prevent potential human harm and environmental pollution risks.