- Appearance: Pale yellow crystalline powder
- Assay: 98.5%~101.0%
- Melting Range: 243~247 °C
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Heavy Metals: ≤10 ppm
- Related Substances: Total impurities ≤1.0%


Applications
Azathioprine is a classic immunosuppressant and important pharmaceutical raw material. It can inhibit the synthesis of purine nucleotides, hinder the proliferation and differentiation of lymphocytes, and effectively suppress abnormal immune response of human body. It is widely used in clinical treatment of autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease and autoimmune hemolytic anemia. Besides, it is commonly used as core immunosuppressive medicine after organ transplantation such as kidney, liver and heart transplantation, which can significantly reduce organ rejection reaction and improve the long-term survival rate of transplanted organs. In pharmaceutical research field, it is used to develop new immune regulation preparations and study immune related disease pathogenesis. It also serves as a standard reference substance for drug detection and quality control. With stable pharmacological effect and mature clinical application, this product occupies an important position in immunosuppressive drug market, and is widely produced and applied in pharmaceutical industry all over the world.
Safety Information
This product belongs to toxic pharmaceutical raw material with strong biological activity and certain health hazards. Inhalation of its powder will irritate respiratory tract and cause dizziness and physical discomfort, so operators must wear professional dust-proof respirator and keep working area fully ventilated. Direct skin contact may cause skin allergy, redness and itching, staff need to wear nitrile protective gloves and protective clothing, and clean exposed skin thoroughly after operation. Eye contact will lead to severe stimulation and inflammation, once contacted, rinse eyes continuously with plenty of clean running water for more than 15 minutes and seek medical treatment immediately. Accidental ingestion will seriously affect hematopoietic function and cause gastrointestinal discomfort, do not take any food or water casually and send to hospital for rescue treatment quickly. This product is stable under normal storage condition, but it will decompose and deteriorate under strong light and high temperature. Keep away from strong oxidants and acidic substances during storage and transportation. All waste materials shall be disposed strictly in accordance with medical hazardous waste standards to prevent public health risks and environmental pollution.