3-Boc-3-methylaminoazatidine
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Storage |
Sealed, dry, dark place; -20°C for long-term storage
|
| aliasen |
|
| supplyCapacity |
50000Metric Ton/Month
|
| Solubility |
Soluble in water (5 g/100 mL), soluble in organic solvents like DCM, EA, MeOH
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
- Purity (HPLC): ≥98.0%
- Moisture: ≤0.3%
- Melting Point: 58–62 °C
- Single Impurity: ≤0.5%
- Total Impurities: ≤1.5%
- Residue on Ignition: ≤0.1%
- Heavy Metals: ≤10 ppm
Applications
This is a strained four-membered azetidine heterocyclic building block with N-Boc protection and N-methyl substitution. The high ring strain enables efficient ring-opening/functionalization reactions. Mainly used in pharmaceutical R&D:
- Synthesis of antitumor, anti-inflammatory, and CNS drug intermediates
- Construction of compound libraries for fragment-based drug discovery
- As a key intermediate in click chemistry and cross-coupling reactions
- For custom synthesis of novel azetidine-containing drug candidates
Safety Information
Irritant; low acute toxicity, but handle with care.
- Inhalation: Dust may irritate respiratory tract; cause cough or throat discomfort.
- Skin Contact: May cause mild irritation, redness, or itching.
- Eye Contact: May cause irritation, tearing, or redness; rinse with plenty of water for ≥15 min.
- Ingestion: May cause nausea, vomiting, or gastrointestinal discomfort.
- Operation: Wear nitrile gloves, safety goggles, and dust mask; work in ventilated area.
- Storage: Keep away from strong acids, oxidants, and moisture; store at -20°C for long term.
- Disposal: Treat as hazardous waste; comply with local regulations.
