2-Bromo-6-fluorophenylboronic acid
- Createtime: 2026-04-14
- Updatetime: 2026-04-15
Product Details
| Boiling Point |
324.4±52.0 °C
|
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Storage |
Sealed, dry, room temperature, away from light, avoid moisture and strong oxidants
|
| aliasen |
|
| supplyCapacity |
50000Metric Ton/Month
|
| Solubility |
Slightly soluble in water, soluble in organic solvents such as DMSO, DMF
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Melting Point |
138–143 °C
|
- Assay (HPLC): ≥98.5%
- Melting Point: 138–143 °C
- Loss on Drying: ≤0.3%
- Single Maximum Impurity: ≤0.2%
- Total Impurities: ≤0.8%
- Residue on Ignition: ≤0.1%
- Heavy Metals (Pb): ≤10 ppm


Applications
2-Bromo-6-fluorophenylboronic acid is a high-value halogenated aryl boronic acid intermediate, widely applied in pharmaceutical synthesis, organic coupling reactions and fine chemical R&D. It acts as a key building block for Suzuki-Miyaura cross-coupling reactions, efficiently constructing C-C bonds to synthesize fluorinated aromatic heterocyclic compounds. It is extensively used to manufacture novel targeted drugs, kinase inhibitors, antiviral agents and anti-tumor pharmaceutical intermediates, owing to its stable bromine and fluorine substituted structure that greatly improves molecular bioavailability and metabolic stability. In agrochemical field, it participates in synthesis of high-efficiency, low-toxic fungicides, herbicides and insecticide active molecules. It also serves as essential reagent in material science, preparing organic optoelectronic materials, fluorescent probes and functional aromatic polymers. Additionally, it supports laboratory organic synthesis research, custom fine chemical production and new drug screening development, playing an irreplaceable role in modern heterocyclic drug innovation and advanced organic synthetic industry chain.
Safety Information
This compound is classified as GHS07 Warning irritant, with hazard statements H315, H319 and H335. Inhalation of fine dust irritates respiratory mucosa, causing cough, sore throat and breathing discomfort; long-term repeated inhalation may induce chronic respiratory inflammation. Direct skin contact leads to erythema, itching and allergic dermatitis, irritating sensitive skin severely. Eye exposure causes intense stinging, conjunctival congestion and lacrimation; immediate continuous flushing with plenty of clean water for more than 15 minutes is required. Accidental ingestion results in nausea, abdominal discomfort and gastrointestinal irritation. Operators must work in well-ventilated fume hoods, wearing dust masks, nitrile gloves and safety goggles. Store separately from food, feed and corrosive chemicals. It has high aquatic toxicity (WGK Germany 3), strictly prevent leakage into water environment and soil. Waste residues and packaging shall be disposed in accordance with local hazardous waste management regulations, avoid random emission to protect ecological safety and personal health.