Assay (HPLC/GC) ≥98.0% (area %)
Appearance White to off-white crystalline powder
Melting Point 70–74 °C
Loss on Drying (Water Content) ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Impurities Single impurity ≤0.2%, total impurities ≤1.0%
Identification Consistent with the standard (IR/UV)
4. Main Applications (Detailed)
2-Propenoic acid hydrazide (CAS 3128-32-3) is a versatile organic intermediate with reactive functional groups (acryloyl and hydrazide groups), making it widely used in chemical synthesis, laboratory research, pharmaceutical, and industrial fields.
4.1 Organic Synthesis Intermediate
It serves as a key building block in organic synthesis, primarily used for the preparation of heterocyclic compounds (such as pyrazoles, triazoles, and oxadiazoles) through condensation reactions with carbonyl compounds, aldehydes, and ketones. Its acryloyl group enables polymerization reactions, making it a monomer for the synthesis of functional polymers and copolymers with specific properties (e.g., water solubility, biocompatibility).
4.2 Laboratory Research Reagent
It is commonly used as a research reagent in academic and industrial laboratories. It is utilized in the development of new synthetic methodologies, such as the synthesis of modified polymers, corrosion inhibitors, and enzyme inhibitors. Additionally, it is used in analytical chemistry for the detection and quantification of specific functional groups in organic compounds.
4.3 Pharmaceutical and Fine Chemical Intermediates
It acts as an intermediate in the synthesis of pharmaceutical compounds, including certain antiviral, antibacterial, and anti-inflammatory drugs. Its hydrazide group can form stable complexes with metal ions, which is useful in the development of metal-based pharmaceutical agents. It is also used in the production of fine chemicals, such as specialty dyes and pigments.
4.4 Industrial Applications
In industry, it is used as a corrosion inhibitor for metals, helping to prevent rust and corrosion in metal processing and storage. It is also added to coatings and adhesives to improve their performance, such as enhancing adhesion and water resistance. Additionally, it is used in the textile industry as a cross-linking agent for fabrics, improving their durability and wrinkle resistance.
4.5 Other Applications
It is used in the synthesis of agrochemicals, such as herbicides and fungicides, to enhance their biological activity. It also has potential applications in the field of materials science, such as the preparation of functional materials (e.g., hydrogels, conductive polymers) for various industrial and biomedical uses.
