Shandong Huashang Chemical Co., Ltd.
Product
9-Bromo-3-(2-Bromo Acetyl)-10,11-Dihydro-5H-dibenzo(c,g) Chromen-8(9H)-one
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:1438383-89-1
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance White to off-white crystalline powder
Molecular Weight 450.12
Stability Light-sensitive; stable under dry, sealed conditions; incompatible with strong oxidants, strong bases, and reducing agents
Storage Keep sealed, cool, dry, and dark
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Soluble in DCM, THF, DMF, DMSO; slightly soluble in EtOAc, toluene; insoluble in water
harbor Qingdao,China
minorder 1KG
Molecular Formula C 19 H 14 Br 2 O 3
  • Purity (HPLC): ≥97.0% / ≥99.0%
  • Moisture: ≤0.30%
  • Loss on Drying: ≤0.40%
  • Residue on Ignition: ≤0.10%
  • Single Impurity: ≤0.50%
  • Total Impurities: ≤1.00%

  • Heavy Metals (Pb): ≤10 ppm

  • Velpatasvir (Anti-HCV Drug) Key Intermediate (Core Use)
    Critical building block for synthesizing Velpatasvir, a direct-acting antiviral agent against hepatitis C virus (HCV). It undergoes cyclization, substitution, and coupling reactions to construct the core dibenzochromenone scaffold of Velpatasvir, ensuring high potency and broad genotype coverage for HCV treatment.
  • Antiviral Pharmaceutical Intermediate
    Used in the synthesis of other antiviral drugs targeting RNA viruses (e.g., HCV, dengue, Zika); the dibenzochromenone core enhances binding to viral non-structural proteins (NS5A/NS5B).
  • Heterocyclic Chemistry Building Block
    Serves as a precursor for complex fused-ring systems via nucleophilic substitution (bromo groups) and carbonyl condensation; widely applied in synthetic methodology for polycyclic aromatic compounds.
  • Laboratory Research & Reference Standard
    Employed in pharmaceutical R&D, impurity profiling, and as a reference standard for HPLC analysis in antiviral drug development.
  • Storage: Sealed, cool (2–8 °C), dry, dark, and ventilated; avoid light, moisture, and strong oxidants
  • Packaging: 1g/5g/10g/25g aluminum foil bags or glass bottles; 10mg/25mg/50mg for lab use
  • Shelf Life: 24 months under proper storage