The product is white to off-white crystalline solid. Purity detected by HPLC is not less than 98.0%. Water content is controlled within 0.5%. Residue on ignition is not more than 0.1%. Heavy metals content is lower than 10 ppm.

No obvious impurity peaks in chromatogram, all specifications meet pharmaceutical intermediate grade requirements.

3-Bromo-5-methylpyridine is an important substituted bromopyridine heterocyclic building block.

It possesses active bromine functional group on pyridine ring, available for nucleophilic substitution and various cross-coupling reactions. It can be used for Suzuki, Heck, Sonogashira and Buchwald-Hartwig amination reactions for molecular structural modification. It is widely applied as key intermediate in the synthesis of kinase inhibitors, anticancer agents, anti-inflammatory drugs and central nervous system therapeutic compounds. It is also commonly used for medicinal chemistry compound library construction and structure-activity relationship research in new drug development.