The product is white to pale yellow crystalline solid. Purity tested by HPLC or GC is not less than 98.0%. Water content is no more than 0.5%. Residue on ignition is not more than 0.1%. Heavy metals content is less than 10 ppm.

Chromatogram shows no obvious impurity peaks, all indexes meet pharmaceutical intermediate grade standard.

2-Bromo-4-methylpyridine is a classic substituted pyridine heterocyclic building block.

The bromine atom at the 2-position has high reactivity for nucleophilic substitution and various cross-coupling reactions. It can be used for Suzuki coupling, Heck reaction, Sonogashira reaction and Buchwald-Hartwig amination. It is widely applied as key intermediate for synthesis of anticancer drugs, kinase inhibitors, anti-inflammatory agents and central nervous system medicines. Also used in medicinal chemistry compound library construction and structure-activity relationship research, as well as agrochemical fine chemical synthesis.