The product is white to off-white crystalline solid. Purity determined by HPLC is not less than 98.0%. Water content is no more than 0.5%. Residue on ignition is not more than 0.1%. Heavy metals content is lower than 10 ppm.

Chromatogram shows no obvious impurity peaks, all quality indexes comply with pharmaceutical intermediate grade specifications.

5-Bromo-2-chloropyridine is a dihalogenated pyridine heterocyclic building block with two different leaving groups.

It enables selective sequential cross-coupling reactions at bromine and chlorine positions for directional molecular modification. It is widely used in Suzuki, Heck, Sonogashira and Buchwald-Hartwig amination reactions in organic synthesis. It serves as a key intermediate for the research and production of kinase inhibitors, anticancer agents, anti-inflammatory drugs and central nervous system therapeutics. It is also extensively applied in medicinal chemistry compound library synthesis and structure-activity relationship investigation for new drug development.