Shandong Huashang Chemical Co., Ltd.
Product
Tri-tert-butylphosphine tetrafluoroborate
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:98%
  • Cas:131274-22-1
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance White to off-white crystalline powder
Molecular Weight 273.13
aliasen
supplyCapacity 50000Metric Ton/Month
Storage condition Store sealed at 2–8 °C, keep dry and away from light
Solubility Soluble in DCM, DMF, DMSO, ethyl acetate; slightly soluble in methanol; insoluble in water
harbor Qingdao,China
minorder 1KG
Molecular Formula C??H??BrN?O?
Melting point 72–76 °C

The product is white to off-white crystalline powder. The purity tested by HPLC is not less than 98.0%. Water content is no more than 0.5%. Residue on ignition is not more than 0.1%. Heavy metals content is below 10 ppm. No obvious impurity peaks appear in chromatogram, and all indexes meet industrial and pharmaceutical intermediate grade specifications.

This compound is a crucial pyridine heterocyclic intermediate with Boc protected amino and bromo substituents on pyridine ring. It is widely used in pharmaceutical intermediate synthesis and organic chemistry research.

It can participate in Suzuki coupling, Heck reaction and Buchwald-Hartwig amination reactions to construct various substituted pyridine derivatives. It is commonly applied in the research and development of anti-cancer drugs, anti-inflammatory agents and central nervous system medicines.
The Boc protecting group can be easily removed under acidic conditions to expose free amino group, which is convenient for further molecular modification and structural optimization. It is also widely used in compound library synthesis and structure-activity relationship study in medicinal chemistry.