Shandong Huashang Chemical Co., Ltd.
Product
THIOCOLCHICOSIDE
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:602-41-5
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
Boiling Point 929.6±65.0 ℃ @ 760 mmHg
deliveryInfo
Stability Stable under dry & sealed conditions; better stored in dark & cool (2–8 ℃)
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Soluble in water, methanol, DMSO; slightly soluble in ethanol; insoluble in n-hexane
harbor Qingdao,China
minorder 1KG
Density 1.5±0.1 g/cm3
useage Industrial use
appearance Yellow to yellowish-brown solid powder
Flash Point 516.0±34.3 ℃
Melting Point 190–198 ℃

Test Item Specification
Assay (HPLC) ≥98.0% (Pharma grade ≥99.0%)
Appearance Yellow to yellowish-brown powder, uniform
Loss on Drying ≤1.0%
Residue on Ignition ≤0.5%
Heavy Metals (Pb) ≤10 ppm
Arsenic (As) ≤2 ppm
Single Impurity ≤1.0%
Total Impurities ≤2.0%
IR Identification

Conforms to reference standard

  • CAS No.:602-41-5
  • Name:Thiocolchicoside
  • Synonyms:Thiocolchicoside (98%), Coltramyl, 10-Thiocolchicoside
  • FormulaC27H33NO10S
  • Molecular Weight563.62
  • EINECS:210-017-7
  • Pharmaceutical (Primary Use)

    • Muscle Relaxant:Potently relieves skeletal muscle spasms for neck/shoulder/low back pain, sciatica, and fibromyalgia.
    • Analgesic & Anti-inflammatory:Inhibits inflammatory mediators; effective pain relief with fewer side effects than colchicine.
    • Rheumatic Disorders:Adjuvant therapy for rheumatoid arthritis, ankylosing spondylitis, and chronic pain.
    • Dosage Forms:Oral tablets, injections, topical gels/creams (lower toxicity for topical use).

    2. Pharmaceutical Synthesis Intermediate

    • Key intermediate for colchicine derivatives; used in novel anti-tumor and anti-inflammatory drug synthesis.
    • Sulfur ether bond construction and functional group transformation in peptides and small-molecule drugs.

    3. Veterinary Use

    • Analgesic and muscle relaxant for animal musculoskeletal disorders (e.g., joint pain, soft tissue injuries in horses and dogs).
  • Hazards:Acute toxicity category 3 (oral/inhalation) – H301: Harmful if swallowed; H331: Harmful if inhaled.
  • Contraindications:Contraindicated in pregnancy/lactation; use caution in hepatic/renal impairment; avoid combination with central nervous system depressants.
  • Protection:Wear dust mask, goggles, chemical gloves; ensure adequate ventilation.